By Ashaunta T. Anderson

50 reports each Pediatrician may still comprehend presents key stories that experience formed the present scientific perform of pediatrics. chosen utilizing a rigorous method, the reviews conceal subject matters together with: allergic reaction immunology, behavioral, cardiology, dermatology, endocrinology, ENT, common pediatrics, hematology, infectious sickness, neonatology, nephrology, neurology, oncology, ophthalmology, orthopedics, and pulmonary. for every learn, a concise precis is gifted with an emphasis at the effects and obstacles of the learn, and its implications for perform. An illustrative scientific case concludes every one evaluation, via short details on different suitable stories. this can be one of many in basic terms books of its style to give a set of the main influential medical trials in pediatrics which are exact sufficient for use on rounds, yet nonetheless simply digestible.

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Year Study Began: Data from 1991–​1999 were included (the data were collected retrospectively). Year Study Published: 2002 Study Location: Denmark. Who Was Studied: All children born in Denmark between January 1991 and December 1998 (all Danish children are entered into a national registry at birth). 12 B e h a v i o ra l Who Was Excluded: Children with tuberous sclerosis, Angelman syndrome, fragile X syndrome, and congenital rubella—​a ll of which are associated with autism. Children who emigrated or who died were also excluded.

Although none of these studies has conclusively ruled out a very small link between MMR vaccination and autism, the preponderance of evidence suggests that there is not. One way to respond to these parents would be to explain that numerous studies of high methodological quality have failed to demonstrate a link between the MMR vaccine and autism. While it is impossible to entirely exclude a very small association, it is very likely that there is not. You should also emphasize to the parents that there are clear and proven benefits of the vaccine, and that major professional organizations such as the American Academy of Pediatrics strongly recommend vaccination for all children.

A meta-​ analysis. CMAJ. 2001;165(11):1475. 7. Biederman J et al. Efficacy and tolerability of lisdexamfetamine dimesylate (NRP-​ 104) in children with attention-​deficit/​hyperactivity disorder: a phase III, multicenter, randomized, double-​blind, forced-​dose, parallel-​g roup study. Clin Ther. 2007;29(3):450. Wigal S et al. A double-​blind, placebo-​controlled trial of dexmethylphenidate hydrochloride and d,l-​threo-​methylphenidate hydrochloride in children with attention-​deficit/​hyperactivity disorder.

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